Amplification of poly(I:C)-induced interleukin-6 production in human bronchial epithelial cells by priming with interferon-γ

Abstract Proinflammatory cytokine interleukin (IL)-6 was associated with disease severity in patients with COVID-19. The mechanism underlying the excessive IL-6 production by SARS-Cov-2 infection remains unclear. Respiratory viruses initially infect nasal or bronchial epithelial cells that produce v...

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Bibliografiska uppgifter
Huvudupphovsmän: Norikazu Okuma, Masa-aki Ito, Tomoyoshi Shimizu, Atsuya Hasegawa, Shin’ya Ohmori, Kazuki Yoshida, Isao Matsuoka
Materialtyp: Artikel
Språk:English
Publicerad: Nature Portfolio 2023-11-01
Serie:Scientific Reports
Länkar:https://doi.org/10.1038/s41598-023-48422-9