CDC42 controls the activation of primordial follicles by regulating PI3K signaling in mouse oocytes

CDC42 controls the activation of primordial follicles by regulating PI3K signaling in mouse oocytes

Abstract Background In mammalian females, progressive activation of dormant primordial follicles in adulthood is crucial for the maintenance of the reproductive lifespan. Misregulated activation of primordial follicles leads to various ovarian diseases, such as premature ovarian insufficiency (POI)....

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Bibliographic Details
Main Authors: Hao Yan, Jiawei Zhang, Jia Wen, Yibo Wang, Wanbao Niu, Zhen Teng, Tongtong Zhao, Yanli Dai, Yan Zhang, Chao Wang, Yingying Qin, Guoliang Xia, Hua Zhang
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Biology
Subjects:
CDC42
PI3K signaling
Primordial follicle activation
In vitro activation
Premature ovarian insufficiency
Online Access:http://link.springer.com/article/10.1186/s12915-018-0541-4

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http://link.springer.com/article/10.1186/s12915-018-0541-4

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