Structure of a Holliday junction complex reveals mechanisms governing a highly regulated DNA transaction

Structure of a Holliday junction complex reveals mechanisms governing a highly regulated DNA transaction

The molecular machinery responsible for DNA expression, recombination, and compaction has been difficult to visualize as functionally complete entities due to their combinatorial and structural complexity. We report here the structure of the intact functional assembly responsible for regulating and...

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Bibliographic Details
Main Authors: Gurunathan Laxmikanthan, Chen Xu, Axel F Brilot, David Warren, Lindsay Steele, Nicole Seah, Wenjun Tong, Nikolaus Grigorieff, Arthur Landy, Gregory D Van Duyne
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-05-01
Series:eLife
Subjects:
site-specific recombination
bacteriophage lambda
electron cryo-microscopy
viral excision
viral integration
Online Access:https://elifesciences.org/articles/14313

Internet

https://elifesciences.org/articles/14313

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