Intergenerational Transmission of Enhanced Seizure Susceptibility after Febrile Seizures

Intergenerational Transmission of Enhanced Seizure Susceptibility after Febrile Seizures

Environmental exposure early in development plays a role in susceptibility to disease in later life. Here, we demonstrate that prolonged febrile seizures induced by exposure of rat pups to a hyperthermic environment enhance seizure susceptibility not only in these hyperthermia-treated rats but also...

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Bibliographic Details
Main Authors: Dengchang Wu, Bo Feng, Yunjian Dai, Xiaohua Wu, Bin Chen, Cenglin Xu, Yangshun Tang, Kang Wang, Shihong Zhang, Shuang Wang, Benyan Luo, Zhong Chen
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:EBioMedicine
Subjects:
Febrile seizures
Transgeneration
Seizure susceptibility
DNA methylation
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396417300658

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http://www.sciencedirect.com/science/article/pii/S2352396417300658

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