Using multivariable Mendelian randomization to disentangle the causal effects of lipid fractions.

Using multivariable Mendelian randomization to disentangle the causal effects of lipid fractions.

Previous Mendelian randomization studies have suggested that, while low-density lipoprotein cholesterol (LDL-c) and triglycerides are causally implicated in coronary artery disease (CAD) risk, high-density lipoprotein cholesterol (HDL-c) may not be, with causal effect estimates compatible with the n...

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Bibliographic Details
Main Authors: Stephen Burgess, Daniel F Freitag, Hassan Khan, Donal N Gorman, Simon G Thompson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4193746?pdf=render

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http://europepmc.org/articles/PMC4193746?pdf=render

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