Using multivariable Mendelian randomization to disentangle the causal effects of lipid fractions.
Previous Mendelian randomization studies have suggested that, while low-density lipoprotein cholesterol (LDL-c) and triglycerides are causally implicated in coronary artery disease (CAD) risk, high-density lipoprotein cholesterol (HDL-c) may not be, with causal effect estimates compatible with the n...
Main Authors: | Stephen Burgess, Daniel F Freitag, Hassan Khan, Donal N Gorman, Simon G Thompson |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4193746?pdf=render |
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