The leaderless communication peptide (LCP) class of quorum-sensing peptides is broadly distributed among Firmicutes

Abstract The human pathogen Streptococcus pyogenes secretes a short peptide (leaderless communication peptide, LCP) that mediates intercellular communication and controls bacterial virulence through interaction with its receptor, RopB. Here, we show that LCP and RopB homologues are present in other...

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Bibliographic Details
Main Authors: Shifu Aggarwal, Elaine Huang, Hackwon Do, Nishanth Makthal, Yanyan Li, Eric Bapteste, Philippe Lopez, Charles Bernard, Muthiah Kumaraswami
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41719-3