Humoral autoimmune response against specific collagen type II epitopes in Bulgarian patients with rheumatoid arthritis
Collagen type II (CII) is a strong candidate autoantigen for rheumatoid arthritis (RA) pathogenesis. CII is the main structural protein of synovial cartilage and it is attacked by both antibodies and T-cells during RA disease course. Experiments with mouse models have identified an immunodominant T-...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Plovdiv University Press
2016-04-01
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Series: | Journal of BioScience and Biotechnology |
Subjects: | |
Online Access: | http://www.jbb.uni-plovdiv.bg/documents/27807/1703624/jbb_2016-5%281%29-pages_45-52.pdf |