Humoral autoimmune response against specific collagen type II epitopes in Bulgarian patients with rheumatoid arthritis

Collagen type II (CII) is a strong candidate autoantigen for rheumatoid arthritis (RA) pathogenesis. CII is the main structural protein of synovial cartilage and it is attacked by both antibodies and T-cells during RA disease course. Experiments with mouse models have identified an immunodominant T-...

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Bibliographic Details
Main Authors: Tsvetelina Batsalova, Petya Ivanova, Plamka Antova, Balik Dzhambazov
Format: Article
Language:English
Published: Plovdiv University Press 2016-04-01
Series:Journal of BioScience and Biotechnology
Subjects:
Online Access:http://www.jbb.uni-plovdiv.bg/documents/27807/1703624/jbb_2016-5%281%29-pages_45-52.pdf