Humoral autoimmune response against specific collagen type II epitopes in Bulgarian patients with rheumatoid arthritis

Humoral autoimmune response against specific collagen type II epitopes in Bulgarian patients with rheumatoid arthritis

Collagen type II (CII) is a strong candidate autoantigen for rheumatoid arthritis (RA) pathogenesis. CII is the main structural protein of synovial cartilage and it is attacked by both antibodies and T-cells during RA disease course. Experiments with mouse models have identified an immunodominant T-...

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Bibliographic Details
Main Authors: Tsvetelina Batsalova, Petya Ivanova, Plamka Antova, Balik Dzhambazov
Format: Article
Language:English
Published: Plovdiv University Press 2016-04-01
Series:Journal of BioScience and Biotechnology
Subjects:
rheumatoid arthritis
autoimmune response
collagen type II
epitope-specific antibodies
Online Access:http://www.jbb.uni-plovdiv.bg/documents/27807/1703624/jbb_2016-5%281%29-pages_45-52.pdf

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