Most mitochondrial dGTP is tightly bound to respiratory complex I through the NDUFA10 subunit

Mitochondrial dGTP is mostly bound to an accessory subunit of complex I of the mitochondrial respiratory chain, which may reveal a mechanism linking mitochondrial dNTP availability and oxidative metabolism.

Bibliographic Details
Main Authors: David Molina-Granada, Emiliano González-Vioque, Marris G. Dibley, Raquel Cabrera-Pérez, Antoni Vallbona-Garcia, Javier Torres-Torronteras, Leonid A. Sazanov, Michael T. Ryan, Yolanda Cámara, Ramon Martí
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03568-6