Determinants of phosphatidylinositol-4-phosphate 5-kinase type Iγ90 uropod location in T-lymphocytes and its role in uropod formation

We have previously identified phosphatidylinositol-4-phosphate 5-kinase type I (PIPKI)γ90 as a T cell uropod component. However, the molecular determinants and functional consequences of its localization remain unknown. In this report, we seek to better understand the mechanisms involved in PIPKIγ90...

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Bibliographic Details
Main Authors: Lucia Mathis, Sarah Wernimont, Sarah Affentranger, Anna Huttenlocher, Verena Niggli
Format: Article
Language:English
Published: PeerJ Inc. 2013-08-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/131.pdf