Determinants of phosphatidylinositol-4-phosphate 5-kinase type Iγ90 uropod location in T-lymphocytes and its role in uropod formation
We have previously identified phosphatidylinositol-4-phosphate 5-kinase type I (PIPKI)γ90 as a T cell uropod component. However, the molecular determinants and functional consequences of its localization remain unknown. In this report, we seek to better understand the mechanisms involved in PIPKIγ90...
Main Authors: | Lucia Mathis, Sarah Wernimont, Sarah Affentranger, Anna Huttenlocher, Verena Niggli |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2013-08-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/131.pdf |
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