Crosstalk between 5-methylcytosine and N6-methyladenosine machinery defines disease progression, therapeutic response and pharmacogenomic landscape in hepatocellular carcinoma

Crosstalk between 5-methylcytosine and N6-methyladenosine machinery defines disease progression, therapeutic response and pharmacogenomic landscape in hepatocellular carcinoma

Abstract Background Accumulated evidence highlights the significance of the crosstalk between epigenetic and epitranscriptomic mechanisms, notably 5-methylcytosine (5mC) and N6-methyladenosine (m6A). Herein, we conducted a widespread analysis regarding the crosstalk between 5mC and m6A regulators in...

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Bibliographic Details
Main Authors: Yu Tian, Haijuan Xiao, Yanhui Yang, Pingping Zhang, Jiahui Yuan, Wei Zhang, Lijie Chen, Yibao Fan, Jinze Zhang, Huan Cheng, Tingwei Deng, Lin Yang, Weiwei Wang, Guoyong Chen, Peiqin Wang, Peng Gong, Xing Niu, Xianbin Zhang
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Molecular Cancer
Subjects:
Hepatocellular carcinoma
5-methylcytosine
N6-methyladenosine
Therapeutic response
Pharmacogenomic landscape
Multi-omics
Online Access:https://doi.org/10.1186/s12943-022-01706-6

Internet

https://doi.org/10.1186/s12943-022-01706-6

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