Leishmania donovani Inhibitor of Serine Peptidases 2 Mediated Inhibition of Lectin Pathway and Upregulation of C5aR Signaling Promote Parasite Survival inside Host

Leishmania donovani Inhibitor of Serine Peptidases 2 Mediated Inhibition of Lectin Pathway and Upregulation of C5aR Signaling Promote Parasite Survival inside Host

Leishmania donovani, the causative agent of Indian visceral leishmaniasis has to face several barriers of the immune system inside the mammalian host for its survival. The complement system is one of the first barriers and consists of a well-balanced network of proteases including S1A family serine...

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Bibliographic Details
Main Authors: Sudha Verma, Abhishek Mandal, Md. Yousuf Ansari, Ajay Kumar, Kumar Abhishek, Ayan Kumar Ghosh, Ashish Kumar, Vinod Kumar, Sushmita Das, Pradeep Das
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
ISP2
MBL-associated serine proteases
membrane attacking complex
serine proteases
Leishmania
PI3K
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00063/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00063/full

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