Protocol for purification of cells in their native state using reversible aptamer-antidote pairs

Summary: Cell isolation from complex mixtures is a key step in many clinical and research applications, but standard isolation methods may affect the cell’s biology and are difficult to reverse. Here, we present a method to isolate and restore cells to their native state using an aptamer that binds...

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Bibliographic Details
Main Authors: Martin D. Requena, Bethany Powell Gray, Bruce A. Sullenger
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166723003155