Imaging of redox-imbalance and oxidative stress in kidney in vivo, induced by dietary cholesterol

Imaging of redox-imbalance and oxidative stress in kidney in vivo, induced by dietary cholesterol

We used a mitochondria-penetrating nitroxide, mito-TEMPO, as a contrast probe for imaging of kidney dysfunction in mice, based on the redox-imbalance and oxidative stress in the renal tissues. Kidney dysfunction was triggered by hypercholesterolemia. The mice were divided in three groups: (i) on nor...

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Bibliographic Details
Main Authors: Dessislava Lazarova, Sayaka Shibata, Itsuko Ishii, Genoveva Zlateva, Zhivko Zhelev, Ichio Aoki, Rumiana Bakalova
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
hypercholesterolemia
kidney dysfunction
redox-imbalance
oxidative stress
magnetic resonance imaging
cyclic nitroxides
Online Access:http://dx.doi.org/10.1080/13102818.2019.1573153

Internet

http://dx.doi.org/10.1080/13102818.2019.1573153

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