EFHB is a Novel Cytosolic Ca2+ Sensor That Modulates STIM1-SARAF Interaction

EFHB is a Novel Cytosolic Ca2+ Sensor That Modulates STIM1-SARAF Interaction

Background/Aims: STIM1 and Orai1 are the key components of store-operated Ca2+ entry (SOCE). Among the proteins involved in the regulation of SOCE, SARAF prevents spontaneous activation of SOCE and modulates STIM1 function. Methods: Cytosolic Ca2+ mobilization was estimated in fura-2-loaded cells us...

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Bibliographic Details
Main Authors: Letizia Albarran, Jose J. Lopez, Isaac Jardin, Jose Sanchez-Collado, Alejandro Berna-Erro, Tarik Smani, Pedro J. Camello, Gines M. Salido, Juan A. Rosado
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
EFHB
SARAF
STIM1
Orai1
Calcium entry
Online Access:https://www.karger.com/Article/FullText/495494

Internet

https://www.karger.com/Article/FullText/495494

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