STAG2 promotes the myelination transcriptional program in oligodendrocytes

STAG2 promotes the myelination transcriptional program in oligodendrocytes

Cohesin folds chromosomes via DNA loop extrusion. Cohesin-mediated chromosome loops regulate transcription by shaping long-range enhancer–promoter interactions, among other mechanisms. Mutations of cohesin subunits and regulators cause human developmental diseases termed cohesinopathy. Vertebrate co...

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Bibliographic Details
Main Authors: Ningyan Cheng, Guanchen Li, Mohammed Kanchwala, Bret M Evers, Chao Xing, Hongtao Yu
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-08-01
Series:eLife
Subjects:
cohesin
loop extrusion
transcription
oligodendrocytes
Online Access:https://elifesciences.org/articles/77848

Internet

https://elifesciences.org/articles/77848

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