Challenges and Opportunities for Immunotherapeutic Intervention against Myeloid Immunosuppression in Glioblastoma

Glioblastoma multiforme (GBM), the most common and deadly brain cancer, exemplifies the paradigm that cancers grow with help from an immunosuppressive tumor microenvironment (TME). In general, TME includes a large contribution from various myeloid lineage-derived cell types, including (in the brain)...

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Bibliographic Details
Main Authors: Mark A. Exley, Samantha Garcia, Amelia Zellander, Jenny Zilberberg, David W. Andrews
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/11/4/1069