GLI1 facilitates collagen-induced arthritis in mice by collaborative regulation of DNA methyltransferases

GLI1 facilitates collagen-induced arthritis in mice by collaborative regulation of DNA methyltransferases

Rheumatoid arthritis (RA) is characterized by joint synovitis and bone destruction, the etiology of which remains to be explored. Many types of cells are involved in the progression of RA joint inflammation, among which the overactivation of M1 macrophages and osteoclasts has been thought to be an e...

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Bibliographic Details
Main Authors: Gaoran Ge, Qianping Guo, Ying Zhou, Wenming Li, Wei Zhang, Jiaxiang Bai, Qing Wang, Huaqiang Tao, Wei Wang, Zhen Wang, Minfeng Gan, Yaozeng Xu, Huilin Yang, Bin Li, Dechun Geng
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-11-01
Series:eLife
Subjects:
rheumatoid arthritis
macrophage
osteoclast
GLI1
DNMTs
Online Access:https://elifesciences.org/articles/92142

Internet

https://elifesciences.org/articles/92142

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