Identification of Luteolin as Enterovirus 71 and Coxsackievirus A16 Inhibitors through Reporter Viruses and Cell Viability-Based Screening

Identification of Luteolin as Enterovirus 71 and Coxsackievirus A16 Inhibitors through Reporter Viruses and Cell Viability-Based Screening

Hand, foot and mouth disease (HFMD) is a common pediatric illness mainly caused by infection with enterovirus 71 (EV71) and coxsackievirus A16 (CA16). The frequent HFMD outbreaks have become a serious public health problem. Currently, no vaccine or antiviral drug for EV71/CA16 infections has been ap...

Full description

Bibliographic Details
Main Authors: Lin Xu, Weiheng Su, Jun Jin, Jiawen Chen, Xiaojun Li, Xuyuan Zhang, Meiyan Sun, Shiyang Sun, Peihu Fan, Dong An, Huafei Zhang, Xiguang Zhang, Wei Kong, Tonghui Ma, Chunlai Jiang
Format: Article
Language:English
Published: MDPI AG 2014-07-01
Series:Viruses
Subjects:
enterovirus 71
coxsackievirus A16
luteolin
reporter virus
high‑throughput assay
antiviral drug discovery
Online Access:http://www.mdpi.com/1999-4915/6/7/2778

Internet

http://www.mdpi.com/1999-4915/6/7/2778

Similar Items