Synthesis, crystal structures, and Hirshfeld analysis of three hexahydroquinoline derivatives

Synthesis, crystal structures, and Hirshfeld analysis of three hexahydroquinoline derivatives

Three hexahydroquinoline derivatives were synthesized and crystallized in an effort to study the structure–activity relationships of these calcium-channel antagonists. The derivatives are ethyl 4-(2-methoxyphenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate, C22H27NO4, (I), et...

Full description

Bibliographic Details
Main Authors: Scott A. Steiger, Chun Li, Allen G. Oliver, Nicholas R. Natale
Format: Article
Language:English
Published: International Union of Crystallography 2022-11-01
Series:Acta Crystallographica Section E: Crystallographic Communications
Subjects:
crystal structure
hydrogen bonding
hexahydroquinoline (hhq)
1,4-dihydropyridine (1,4-dhp)
calcium-channel antagonist
multi-drug resistance (mdr)
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2056989022009495

Internet

http://scripts.iucr.org/cgi-bin/paper?S2056989022009495

Similar Items