Evidence of Notch-Hesr-Nrf2 Axis in Muscle Stem Cells, but Absence of Nrf2 Has No Effect on Their Quiescent and Undifferentiated State.

Evidence of Notch-Hesr-Nrf2 Axis in Muscle Stem Cells, but Absence of Nrf2 Has No Effect on Their Quiescent and Undifferentiated State.

Nrf2 is a master regulator of oxidative stresses through the induction of anti-oxidative genes. Nrf2 plays roles in maintaining murine hematopoietic stem cells and fly intestinal stem cells. The canonical Notch signaling pathway is also crucial for maintaining several types of adult stem cells inclu...

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Bibliographic Details
Main Authors: Masahiko Yamaguchi, Satoshi Murakami, Tomohiro Yoneda, Miki Nakamura, Lidan Zhang, Akiyoshi Uezumi, Sumiaki Fukuda, Hiroki Kokubo, Kazutake Tsujikawa, So-Ichiro Fukada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4587955?pdf=render

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http://europepmc.org/articles/PMC4587955?pdf=render

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