Targeting the extra domain A of fibronectin for cancer therapy with CAR-T cells

Targeting the extra domain A of fibronectin for cancer therapy with CAR-T cells

Background One of the main difficulties of adoptive cell therapies with chimeric antigen receptor (CAR)-T cells in solid tumors is the identification of specific target antigens. The tumor microenvironment can present suitable antigens for CAR design, even though they are not expressed by the tumor...

Full description

Bibliographic Details
Main Authors: Felipe Prosper, Sandra Hervás-Stubbs, Juan Jose Lasarte, Noelia Casares, Teresa Lozano, Diego Serrano, Carlos E De Andrea, Alfonso Calvo, Enrique Conde, Celia Martín-Otal, Aritz Lasarte-Cia, Flor Navarro, Inés Sánchez-Moreno, Marta Gorraiz, Patricia Sarrión, José Echeveste, Amaia Vilas, Juan Roberto Rodriguez-Madoz, Jesús San Miguel
Format: Article
Language:English
Published: BMJ Publishing Group 2022-08-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/10/8/e004479.full

Internet

https://jitc.bmj.com/content/10/8/e004479.full

Similar Items