Detection and quantification of the giant protein titin by SDS-agarose gel electrophoresis

Titin, a giant sarcomeric protein, is involved in the generation of passive tension during muscle contraction, assembly and stability of the sarcomere in striated muscles. Titin gene produces numerous titin protein isoforms with different sizes (∼3–4 MDa) resulting from alternative splicing. To stud...

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Bibliographic Details
Main Authors: Chaoqun Zhu, Wei Guo
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:MethodsX
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2215016117300377