Anti-apoptotic proteins in the autophagic world: an update on functions of XIAP, Survivin, and BRUCE

Abstract X-linked inhibitor of apoptosis protein (XIAP), survivin, and BRUCE are members of the inhibitor-of-apoptosis protein (IAP) family known for their inhibitory effects on caspase activity and dysregulation of these molecules has widely been shown to cause embryonic defects and to promote tumo...

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Bibliographic Details
Main Authors: Chun Hei Antonio Cheung, Yung-Chieh Chang, Tzu-Yu Lin, Siao Muk Cheng, Euphemia Leung
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Journal of Biomedical Science
Subjects:
Online Access:https://doi.org/10.1186/s12929-020-0627-5