Neoepitope fragments as biomarkers for different phenotypes of intervertebral disc degeneration

Neoepitope fragments as biomarkers for different phenotypes of intervertebral disc degeneration

Abstract Background During the intervertebral disc (IVD) degeneration process, initial degenerative events occur at the extracellular matrix level, with the appearance of neoepitope peptides formed by the cleavage of aggrecan and collagen. This study aims to elucidate the spatial and temporal altera...

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Bibliographic Details
Main Authors: Shangbin Cui, Wenyue Li, Graciosa Q. Teixeira, Cornelia Neidlinger‐Wilke, Hans‐Joachim Wilke, Lisbet Haglund, Hongwei Ouyang, R. Geoff Richards, Sibylle Grad, Mauro Alini, Zhen Li
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:JOR Spine
Subjects:
biomarker
bioreactor
intervertebral disc degeneration
neoepitope
organ culture model
Online Access:https://doi.org/10.1002/jsp2.1215

Internet

https://doi.org/10.1002/jsp2.1215

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