Neoepitope fragments as biomarkers for different phenotypes of intervertebral disc degeneration
Abstract Background During the intervertebral disc (IVD) degeneration process, initial degenerative events occur at the extracellular matrix level, with the appearance of neoepitope peptides formed by the cleavage of aggrecan and collagen. This study aims to elucidate the spatial and temporal altera...
Main Authors: | Shangbin Cui, Wenyue Li, Graciosa Q. Teixeira, Cornelia Neidlinger‐Wilke, Hans‐Joachim Wilke, Lisbet Haglund, Hongwei Ouyang, R. Geoff Richards, Sibylle Grad, Mauro Alini, Zhen Li |
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Format: | Article |
Language: | English |
Published: |
Wiley
2022-09-01
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Series: | JOR Spine |
Subjects: | |
Online Access: | https://doi.org/10.1002/jsp2.1215 |
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