Characterization of the Therapeutic Effects of Novel Chimeric Antigen Receptor T Cells Targeting CD38 on Multiple Myeloma

Characterization of the Therapeutic Effects of Novel Chimeric Antigen Receptor T Cells Targeting CD38 on Multiple Myeloma

Multiple myeloma (MM) is a tumor type characterized by the unregulated proliferation of clonal plasma cells in the bone marrow. Immunotherapy based on chimeric antigen receptor T cell (CAR-T) therapy has achieved exciting success in the treatment of hematological malignant tumors. CD38 is highly and...

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Bibliographic Details
Main Authors: Xiaorui Li, Yaru Feng, Fengqin Shang, Zhuoying Yu, Tieshan Wang, Jing Zhang, Zhiru Song, Ping Wang, Bingjie Shi, Jianxun Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Oncology
Subjects:
chimeric antigen receptor
CAR-T
CD38
multiple myeloma
immunotherapy
xenograft
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.703087/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.703087/full

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