Testing assembly strategies of Francisella tularensis genomes to infer an evolutionary conservation analysis of genomic structures

Testing assembly strategies of Francisella tularensis genomes to infer an evolutionary conservation analysis of genomic structures

Abstract Background We benchmarked sequencing technology and assembly strategies for short-read, long-read, and hybrid assemblers in respect to correctness, contiguity, and completeness of assemblies in genomes of Francisella tularensis. Benchmarking allowed in-depth analyses of genomic structures o...

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Bibliographic Details
Main Authors: Kerstin Neubert, Eric Zuchantke, Robert Maximilian Leidenfrost, Roebbe Wuenschiers, Josephine Grützke, Burkhard Malorny, Holger Brendebach, Sascha Al Dahouk, Timo Homeier, Helmut Hotzel, Knut Reinert, Herbert Tomaso, Anne Busch
Format: Article
Language:English
Published: BMC 2021-11-01
Series:BMC Genomics
Subjects:
Francisella pathogenicity island
Insertion sequences
High-throughput sequencing
Short-read assembly
Hybrid assembly
Ion Torrent’s ion S5
Online Access:https://doi.org/10.1186/s12864-021-08115-x

Internet

https://doi.org/10.1186/s12864-021-08115-x

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