The sustained-release agent of total flavonoids of Rhizoma drynariae prepared by nano-mesoporous silica can still promote osteogenesis and angiogenesis in vitro

The sustained-release agent of total flavonoids of Rhizoma drynariae prepared by nano-mesoporous silica can still promote osteogenesis and angiogenesis in vitro

Abstract Total flavonoids of Rhizoma drynariae (TFRD) possess the ability to enhance bone formation by promoting the coupling of angiogenesis and osteogenesis. However, the limited duration of serum concentration necessitates frequent oral administration. Designing TFRD as a sustained-release agent...

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Bibliographic Details
Main Authors: XiuHong Huang, ChiHung Li, YiuMan Lau, ZiLing Lin, ChongZhi OuYang, LiQin Zheng
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Total flavonoids of Rhizoma drynariae
Angiogenesis
Osteogenesis
Mesoporous silica
Sustained-release agent
Online Access:https://doi.org/10.1038/s41598-025-88137-7

Internet

https://doi.org/10.1038/s41598-025-88137-7

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