A noncanonical function of histidyl‐tRNA synthetase: inhibition of vascular hyperbranching during zebrafish development

Histidyl‐tRNA synthetase (Hars) catalyzes the ligation of histidine residues to cognate tRNA. Here, we demonstrate a noncanonical function of Hars in vascular development in zebrafish. We obtained a novel zebrafish cq34 mutant which exhibited hyperbranching of cranial and intersegmental blood vessel...

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Bibliographic Details
Main Authors: Rui Ni, Lingfei Luo
Format: Article
Language:English
Published: Wiley 2018-05-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.12420