Comparison of metagenomic next-generation sequencing using cell-free DNA and whole-cell DNA for the diagnoses of pulmonary infections

Comparison of metagenomic next-generation sequencing using cell-free DNA and whole-cell DNA for the diagnoses of pulmonary infections

Although the fast-growing metagenomic next-generation sequencing (mNGS) has been used in diagnosing infectious diseases, low detection rate of mNGS in detecting pathogens with low loads limits its extensive application. In this study, 130 patients with suspected pulmonary infections were enrolled, f...

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Bibliographic Details
Main Authors: Ping He, Jing Wang, Rui Ke, Wei Zhang, Pu Ning, Dexin Zhang, Xia Yang, Hongyang Shi, Ping Fang, Zongjuan Ming, Wei Li, Jie Zhang, Xilin Dong, Yun Liu, Jiemin Zhou, Han Xia, Shuanying Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
MNGs
cell-free DNA
whole-cell DNA
pulmonary infection
BALF
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.1042945/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.1042945/full

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