A systematic review and meta-analysis demonstrating Klotho as an emerging exerkine

Abstract Klotho is an anti-aging protein with several therapeutic roles in the pathophysiology of different organs, such as the skeletal muscle and kidneys. Available evidence suggests that exercise increases Klotho levels, regardless of the condition or intervention, shedding some light on this ant...

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Bibliographic Details
Main Authors: Hugo de Luca Corrêa, Artur Temizio Oppelt Raab, Thamires Marra Araújo, Lysleine Alves Deus, Andrea Lucena Reis, Fernando Sousa Honorato, Paolo Lucas Rodrigues-Silva, Rodrigo Vanerson Passos Neves, Henver Simionato Brunetta, Marcelo Alves da Silva Mori, Octávio Luiz Franco, Thiago dos Santos Rosa
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-22123-1