The Association between the Abundance of Homozygous Deleterious Variants and the Morbidity of Dog Breeds

It is well known that highly inbred dogs are more prone to diseases than less inbred or outbred dogs. This is because inbreeding increases the load of recessive deleterious variants. Using the genomes of 392 dogs belonging to 83 breeds, we investigated the association between the abundance of homozy...

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Bibliographic Details
Main Authors: Sankar Subramanian, Manoharan Kumar
Format: Article
Language:English
Published: MDPI AG 2024-07-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/13/8/574