Genetic Variants and Protein Alterations of Selenium- and T-2 Toxin-Responsive Genes Are Associated With Chondrocytic Damage in Endemic Osteoarthropathy

Genetic Variants and Protein Alterations of Selenium- and T-2 Toxin-Responsive Genes Are Associated With Chondrocytic Damage in Endemic Osteoarthropathy

The mechanism of environmental factors in Kashin–Beck disease (KBD) remains unknown. We aimed to identify single nucleotide polymorphisms (SNPs) and protein alterations of selenium- and T-2 toxin–responsive genes to provide new evidence of chondrocytic damage in KBD. This study sampled the cubital v...

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Bibliographic Details
Main Authors: Yujie Ning, Minhan Hu, Jiayu Diao, Yi Gong, Ruitian Huang, Sijie Chen, Feiyu Zhang, Yanli Liu, Feihong Chen, Pan Zhang, Guanghui Zhao, Yanhai Chang, Ke Xu, Rong Zhou, Cheng Li, Feng Zhang, Mikko Lammi, Xi Wang, Xiong Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Genetics
Subjects:
single nucleotide polymorphism
Kashin–Beck disease
chondrocyte damage
selenium
T-2 toxin
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.773534/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.773534/full

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