Heterozygous HbAC but not HbAS is associated with higher newborn birthweight among women with pregnancy-associated malaria

Abstract Pregnancy-associated malaria (PAM) is associated with poor pregnancy outcomes. Hemoglobin S (HbS) and hemoglobin C (HbC) mutations are frequently encountered in malaria-endemic areas of Africa, where they protect children from severe and uncomplicated Plasmodium falciparum malaria. However,...

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Bibliographic Details
Main Authors: Marilou Tétard, Jacqueline Milet, Sébastien Dechavanne, Nadine Fievet, Dominique Dorin-Semblat, Jacques Elion, Rick M. Fairhurst, Philippe Deloron, Nicaise Tuikue-Ndam, Benoît Gamain
Format: Article
Language:English
Published: Nature Portfolio 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01495-9