TRPC4 deletion elicits behavioral defects in sociability by dysregulating expression of microRNA-138-2
Summary: To investigate whether the defects in transient receptor potential canonical 4 (TRPC4), which is strongly expressed in the hippocampus, are implicated in ASD, we examined the social behaviors of mice in which Trpc4 was deleted (Trpc4−/−). Trpc4−/− mice displayed the core symptoms of ASD, na...
| Autori principali: | , , , , , , , , |
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| Natura: | Articolo |
| Lingua: | English |
| Pubblicazione: |
Elsevier
2024-01-01
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| Serie: | iScience |
| Soggetti: | |
| Accesso online: | http://www.sciencedirect.com/science/article/pii/S2589004223026949 |