Dlk2 interacts with Syap1 to activate Akt signaling pathway during osteoclast formation
Abstract Excessive osteoclast formation and bone resorption are related to osteolytic diseases. Delta drosophila homolog-like 2 (Dlk2), a member of the epidermal growth factor (EGF)-like superfamily, reportedly regulates adipocyte differentiation, but its roles in bone homeostasis are unclear. In th...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-09-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-023-06107-1 |