Extracellular Vesicles Isolated from Malignant Mesothelioma Cancer-Associated Fibroblasts Induce Pro-Oncogenic Changes in Healthy Mesothelial Cells

Extracellular Vesicles Isolated from Malignant Mesothelioma Cancer-Associated Fibroblasts Induce Pro-Oncogenic Changes in Healthy Mesothelial Cells

Malignant mesothelioma is an aggressive tumour of the pleura (MPM) or peritoneum with a clinical presentation at an advanced stage of the disease. Current therapies only marginally improve survival and there is an urgent need to identify new treatments. Carcinoma-associated fibroblasts (CAFs) repres...

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Bibliographic Details
Main Authors: Tatyana Chernova, Stefano Grosso, Xiao-Ming Sun, Angela Rubio Tenor, Joaquin Zacarias Cabeza, Andrew Craxton, Emily L. Self, Apostolos Nakas, Kelvin Cain, Marion MacFarlane, Anne E. Willis
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
cancer
asbestos
mesothelioma
fibroblasts
extracellular vesicles
tumour microenvironment
Online Access:https://www.mdpi.com/1422-0067/23/20/12469

Internet

https://www.mdpi.com/1422-0067/23/20/12469

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