Attenuated succinate accumulation relieves neuronal injury induced by hypoxia in neonatal mice

Abstract Hypoxia causes neonatal neuronal damage. However, the underlying mechanism remains unclear. This study aimed to explore the changes in succinate levels and identify the mechanisms underlying their contribution to hypoxia-induced damage in newborn mice. The neonatal C57BL/6J mouse hypoxia mo...

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Bibliographic Details
Main Authors: Mengdi Zhang, Yao Cheng, Yujie Zhai, Yaru Cui, Wenshen Zhang, Hongwei Sun, Wenyu Xin, Ling Zhou, Xue Gao, Shucui Li, Hongliu Sun
Format: Article
Language:English
Published: Nature Publishing Group 2022-03-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-00940-7