Mechanosensitive accumulation of non-muscle myosin IIB during mitosis requires its translocation activity

Summary: Non-muscle myosin II (NMII) is a force-generating mechanosensitive enzyme that responds to mechanical forces. NMIIs mechanoaccumulate at the cell cortex in response to mechanical forces. It is essential for cells to mechanically adapt to the physical environment, failure of which results in...

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Bibliographic Details
Main Authors: Chao Wang, Jingjing Ding, Qiaodong Wei, Shoukang Du, Xiaobo Gong, Ting Gang Chew
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223018503