TP53 mutation detected in circulating exosomal DNA is associated with prognosis of patients with hepatocellular carcinoma

TP53 mutation detected in circulating exosomal DNA is associated with prognosis of patients with hepatocellular carcinoma

Exosome DNA (exoDNA) can be used for liquid biopsy. This study was the first to use droplet digital PCR (ddPCR) to detect tumor-specific mutations in exoDNA and to evaluate the prognosis of hepatocellular carcinoma (HCC) patients. 60 HCC patients were enrolled in the study. We used ddPCR to detect c...

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Bibliographic Details
Main Authors: Yong Li, Junjun Wu, Enliang Li, Zhouqing Xiao, Jun Lei, Fan Zhou, Xiangbao Yin, Dandan Hu, Yilei Mao, Linquan Wu, Liao Wenjun
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Cancer Biology & Therapy
Subjects:
liquid biopsy
exosomal dna
hepatocellular carcinoma
droplet digital pcr
tp53 mutation
Online Access:http://dx.doi.org/10.1080/15384047.2022.2094666

Internet

http://dx.doi.org/10.1080/15384047.2022.2094666

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