Association of the malate dehydrogenase-citrate synthase metabolon is modulated by intermediates of the Krebs tricarboxylic acid cycle

Abstract Mitochondrial malate dehydrogenase (MDH)-citrate synthase (CS) multi-enzyme complex is a part of the Krebs tricarboxylic acid (TCA) cycle ‘metabolon’ which is enzyme machinery catalyzing sequential reactions without diffusion of reaction intermediates into a bulk matrix. This complex is ass...

Cijeli opis

Bibliografski detalji
Glavni autori: Joy Omini, Izabela Wojciechowska, Aleksandra Skirycz, Hideaki Moriyama, Toshihiro Obata
Format: Članak
Jezik:English
Izdano: Nature Portfolio 2021-09-01
Serija:Scientific Reports
Online pristup:https://doi.org/10.1038/s41598-021-98314-z