Oxidative Stress-mediated HMGB1 Biology

High mobility group box 1 (HMGB1) is a widely-expressed and highly-abundant protein that acts as an extracellular signal upon active secretion by immune cells or passive release by dead, dying, and injured cells. Both intracellular and extracellular HMGB1 play pivotal roles in regulation of the cell...

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Bibliographic Details
Main Authors: Yan eYu, Daolin eTang, Rui eKang
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00093/full