Saturation Mutagenesis for Phenylalanine Ammonia Lyases of Enhanced Catalytic Properties

Saturation Mutagenesis for Phenylalanine Ammonia Lyases of Enhanced Catalytic Properties

Phenylalanine ammonia-lyases (PALs) are attractive biocatalysts for the stereoselective synthesis of non-natural phenylalanines. The rational design of PALs with extended substrate scope, highlighted the substrate specificity-modulator role of residue I460 of <i>Petroselinum crispum</i>...

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Bibliographic Details
Main Authors: Raluca Bianca Tomoiagă, Souad Diana Tork, Ilka Horváth, Alina Filip, Levente Csaba Nagy, László Csaba Bencze
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Biomolecules
Subjects:
biocatalysis
phenylalanine ammonia-lyases
saturation mutagenesis
protein engineering
Online Access:https://www.mdpi.com/2218-273X/10/6/838

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https://www.mdpi.com/2218-273X/10/6/838

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