Red light-emitting diode light mediated by the KEAP1-NRF2/HO-1 pathway induces osteogenic differentiation and attenuates the oxidative stress damage of human periodontal ligament stem cells induced by high glucose

Red light-emitting diode light mediated by the KEAP1-NRF2/HO-1 pathway induces osteogenic differentiation and attenuates the oxidative stress damage of human periodontal ligament stem cells induced by high glucose

摘要 目的 探讨Kelch样ECH相关蛋白1-核因子E2相关因子2/血红素加氧酶-1（Kelch-like ECH associated protein 1-nuclear factor erythroid 2-related factor 2/heme oxygenase-1，KEAP1-NRF2/HO-1）通路介导发光二极管（light-emitting diode，LED）红光对高糖诱导下人牙周膜干细胞（human periodontal ligament stem cells，hPDLSCs）成骨分化和氧化损伤的影响，为LED红光在细胞抗氧化损伤中的应用提供依据。方法 流式细胞术、碱...

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Bibliographic Details
Main Authors: JIANG Bing, FENG Maogeng, ZHENG Genzi, LIU Yuan, LI Hao, WANG Yao
Format: Article
Language:zho
Published: Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases 2023-06-01
Series:口腔疾病防治
Subjects:
light-emitting diode
human periodontal ligament stem cells
high glucose
osteogenic differentiation
reactive oxygen species
antioxidant
kelch-like ech associated protein 1
nuclear factor erythroid 2-related factor 2
heme oxygenase-1
Online Access:http://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2023.06.002

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http://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2023.06.002

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