Molecular Mechanisms Underlying the Elevated Expression of a Potentially Type 2 Diabetes Mellitus Associated SCD1 Variant

Molecular Mechanisms Underlying the Elevated Expression of a Potentially Type 2 Diabetes Mellitus Associated SCD1 Variant

Disturbances in lipid metabolism related to excessive food intake and sedentary lifestyle are among major risk of various metabolic disorders. Stearoyl-CoA desaturase-1 (SCD1) has an essential role in these diseases, as it catalyzes the synthesis of unsaturated fatty acids, both supplying for fat st...

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Bibliographic Details
Main Authors: Kinga Tibori, Gabriella Orosz, Veronika Zámbó, Péter Szelényi, Farkas Sarnyai, Viola Tamási, Zsolt Rónai, Judit Mátyási, Blanka Tóth, Miklós Csala, Éva Kereszturi
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
stearoyl-CoA desaturase-1
single nucleotide polymorphism
fatty acids
type 2 diabetes mellitus
oleate
lipotoxicity
Online Access:https://www.mdpi.com/1422-0067/23/11/6221

Internet

https://www.mdpi.com/1422-0067/23/11/6221

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