Association between the <it>Cytotoxic T-Lymphocyte Antigen 4 </it>+49G > A polymorphism and cancer risk: a meta-analysis

<p>Abstract</p> <p>Background</p> <p>As a key gene in the immunosurveillance of cell malignancy, Cytotoxic T-lymphocyte antigen 4 (CTLA-4 is an important negative regulator of T cell activation and proliferation. The CTLA-4 +49G > A polymorphism is one of the most co...

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Bibliographic Details
Main Authors: Lu Jiachun, Bai Bing, Xiao Mang, Jiang Lan, Yu Xiao, Zheng Jian, Zhou Yifeng
Format: Article
Language:English
Published: BMC 2010-10-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/522