Investigation of the Anti-Methicillin-Resistant <i>Staphylococcus aureus</i> Activity of (+)-Tanikolide- and (+)-Malyngolide-Based Analogues Prepared by Asymmetric Synthesis

Investigation of the Anti-Methicillin-Resistant <i>Staphylococcus aureus</i> Activity of (+)-Tanikolide- and (+)-Malyngolide-Based Analogues Prepared by Asymmetric Synthesis

Herein, we report antibacterial and antifungal evaluation of a series of previously prepared (+)-tanikolide analogues. One analogue, (4<i>S</i>,6<i>S</i>)-4-methyltanikolide, displayed promising anti-methicillin-resistant <i>Staphylococcus aureus</i> activity with...

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Bibliographic Details
Main Authors: Joseph Breheny, Cian Kingston, Robert Doran, Joao Anes, Marta Martins, Séamus Fanning, Patrick J. Guiry
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
(+)-tanikolide
(−)-malyngolide
asymmetric synthesis
anti-methicillin-resistant <i>Staphylococcus aureus</i> activity
Online Access:https://www.mdpi.com/1422-0067/22/12/6400

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https://www.mdpi.com/1422-0067/22/12/6400

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